Interactive Case Study - March 2017

Question 1:

A 23-year-old immunocompromised female presents with 3 month history of asymptomatic 3cm erythematous, indurated flat plaque of the right medial thigh.  

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Figure 1. 2x upper


Figure 2. 2x lower

Figure 3. 10x 2


Figure 4. 20x


Figure 5. 40x

 
Which of the following is the best diagnosis?

A.  Alpha-1 antitrypsin deficiency-associated panniculitis

B.  Cold panniculitis

C.  Histiocytoid Sweet syndrome

D.  Infectious panniculitis

E.  Palisaded neutrophilic and granulomatous dermatitis (interstitial granulomatous dermatitis)