The American Society of Dermatopathology


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Interactive Case Study - October 2016

90-year-old female with breast erythema and axillary lymphadenopathy

Joel Tjarks, MD; Douglas W. Lynch, MD


Question 1:

A 90-year-old female presented to her primary physician with breast tenderness and erythema. Axillary lymphadenopathy was found on physical exam, and the clinician was highly suspicious for inflammatory breast carcinoma.

Click this image to view the virtual slide.

Figure 1. 4x


Figure 2. 20x


Figure 3. 20x


Figure 4. 60x


Figure 5. CD3


Figure 6. CD20


Figure 7. CD4


Figure 8. CD8


Figure 9. CD30


Figure 10. Axillary lymph node 4x


Figure 11. Axillary lymph node 10x


Figure 12. Axillary lymph node 20x


Figure 13. Axillary lymph node 60x


Figure 14. Axillary lymph node CD4


Figure 15. Axillary lymph node CD8


Figure 16. Axillary lymph node CD30


Figure 17. Axillary lymph node EBER

What is the best diagnosis?