Question 1:
A 56-year-old woman presented to clinic for evaluation of an eschar surrounded by tender papules on the right lower extremity. She also had fever and inguinal lymphadenopathy. On further questioning, she reported recent travel to South Africa and East Africa. The histopathology is shown below in Figures 1-3.
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Figure 1. 2x
Figure 2. 10x
Figure 3. 40x
What is the best diagnosis?