Interactive Case Study - February 2015

Painless periorbital mass

Amanda F. Marsch, MD; Razan Massarani-Wafai, MD; Kelli Ann Hutchens, MD

A 50-year-old male presented with a slowly growing, painless periorbital mass of two-year duration. Excisional biopsy demonstrated the following histopathology (Figures 1-6).

Click this image to view the virtual slide for this case:

Figure 1. 1x

Figure 2. 5x

Figure 3. 3x

Figure 4. 8x

Figure 5. 6x

Figure 6. 18x

What is the best diagnosis?

A.	Multinucleate cell angiohistiocytoma

B.	Giant cell fibroblastoma

C.	Vascular malformation

D.	Prolapsed orbital fat

E.	Giant cell angiofibroma