Interactive Case Study - February 2014

Question 1:

A 62-year-old male presented with a 2.5 cm x 5 cm tan patch with speckled dark brown-black macules on his left shoulder (Figure 1). The lesion was asymptomatic and had been present since adolescence. The histopathology is shown below (Figure 2-9)

Figure 1. Clinical photo

Figure 2. H&E

Figure 3. H&E

Figure 4. H&E

Figure 5. H&E

Figure 6. S100

Figure 7. HMB-45

Figure 8. CD34

Figure 9. EMA

What is your diagnosis?

A.  Nevus spilus

B.  Neurocristic hamartoma

C.  Congenital nevus

D.  Nevus of Ito

E.  Common blue nevus