Interactive Case Study - May 2023

Question 1:

A healthy 21-month-old male infant presented with a tan-brown nodular lesion on his left anterior chest wall and a hairless, brown patch on his scalp. A surgical excision was performed.

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Figure 1: H&E 20X


Figure 2: H&E 40X


Figure 3: H&E 200X


Figure 4: H&E 400X

Which of the following is the best diagnosis?

A.	Café au lait macule

B.	Cutaneous mastocytosis

C.	Juvenile xanthogranuloma

D.	Langerhans cell histiocytosis

E.	Melanocytic nevus