Question 1:
A 72-year-old man presented with a new, solitary lesion located at the left medial canthus, involving the caruncle, which had persisted for a month. His past medical history included Parkinson Disease, hyperlipidemia, and anxiety for which he was taking appropriate medications. Physical exam revealed an erythematous papule with mild pruritus and irritation on the left caruncle (Figure 1). Biopsy of the lesion revealed the following histopathology (Figures 2-4).
Click this image to view the virtual slide.
Figure 1. Papule in medial canthus
Figure 2. H&E, 40x
Figure 3. H&E, 200x
Figure 4. H&E, 600x
What is the most likely diagnosis?