The American Society of Dermatopathology


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Interactive Case Study - January 2022

‎60-year-old woman with a tender, rapidly growing nodule

Jaffar Khan, MBBS; Ahmed Khalid Alomari‎, MD


Question 1:

A 60-year-old woman presented with a tender, rapidly growing nodule in her chest. A deep punch biopsy was performed.

Click this image to view the virtual slide


Figure 1. Clinical image


Figure 2. H&E, low power


Figure 3. H&E, high power


Figure 4. CK20, high power


Figure 5. CK7, high power


Figure 6.TTF-1, high power

 
What is the best diagnosis?