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The American Society of Dermatopathology
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Interactive Case Study - October 2021
An enlarging right arm mass in a 7-month-old male
Anna Agaronov, OMS-III; Narciss Mobini, MD
Question 1:
A 7-month-old male presented with a right arm mass that had been growing for the past 4 months. Clinical differential diagnoses included lipoma, hemangioma, or rhabdomyosarcoma and the imaging studies including MRI, ultrasound, and doppler flows suggested the lesion to be either a hemangioma or rhabdomyosarcoma. A biopsy of the lesion revealed the following histopathologic changes:
Click the picture below to view the virtual slide.
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Which of the following is the best diagnosis?
A.
Calcifying aponeurotic fibroma
B.
Cellular dermatofibroma
C.
Fibrous hamartoma of infancy
D.
Infantile myofibromatosis/myofibroma
E.
Plexiform fibrohistiocytic tumor