Interactive Case Study - July 2021

Question 1:

A 36-year-old women presents with a 3-month history of new skin findings affecting her left hip. Clinical exam reveals a painless, well-circumscribed, atrophic-appearing plaque with a faint violaceous hue, which was most prominent at the periphery of the lesion (Figure 1). She denies any significant medical history or recent injury. A punch biopsy of the area showed the following histopathology (Figure 2 - 6). An additional punch biopsy of nearby normal skin was also performed (Figure 7 - 8).

Figure 1.


Figure 2.


Figure 3.


Figure 4.


Figure 5.


Figure 6.


Figure 7.


Figure 8.


 
What is the most likely diagnosis?

A.  Liposarcoma

B.  Localized lipodystrophy

C.  Lupus panniculitis

D.  Partial lipodystrophy

E.  Traumatic panniculitis