Interactive Case Study - January 2020

Question 1:

A 32-year-old Hispanic female presents with a 2.5cm well circumscribed, red-brown nodular growth on the left nasolabial fold. The lesion had been steadily increasing in size over the past year and is otherwise asymptomatic (Figure1). Biopsies of the lesion revealed the following histopathologic changes (Figures 2-5):
 
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Figure 1

 
Figure 2

 
Figure 3A

 
Figure 3B

 
Figure 4

 
Figure 5


 
Which of the following is the best diagnosis?
 

A.	Granulomatous rosacea, exuberant

B.	Lepromatous leprosy

C.	Multicentric reticulohistiocytoma

D.	Rosai-Dorfman Disease

E.	Xanthogranuloma, adult type